Re: A challenging panhypopituitarism case

From: <androlog@godot.urol.uic.edu>
Date: Wed Feb 04 2009 - 06:14:13 CST

Androlog Mail

Dr. Shefi presented an interesting case of hypogonadotropic hypogonadism
where endogenous testosterone production didn't seem to occur despite HCG
treatment.

I suggest performing an HCG stimulation test (total testosterone before and
the day after 3 daily HCG 5000 units injections).

The protocol we use for treating hypogonadotropic hypogonadism starts with
75 IU FSH (3 IM injections /week) + 2500 IU HCG (2 /week) and increase the
FSH to 150 IU (3/ week) if spermatogenesis isn't initiated within 6 months.
Testicular sperm extraction should not be needed as patients with
hypogonadotropic hypogonadism will almost always respond to FSH / HCG
therapy given in sufficient dosages and duration.

Best regards,

Hussein Ghanem, M.D.
Professor of Andrology, Sexology & STDs
Cairo University, Cairo, Egypt
hmghanem@hotmail.com
Received on Wed Feb 4 06:14:13 2009

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