Androlog Mail
In response to Dr. Meacham's questions {about 100% non-motile sperm}:
1) How optimistic are you that HOS (or other techniques) would reliably
identify sperm suitable for ICSI in a case such as this? I am very
optimistic that if the plasma membrane is functional then a coiled tail will
result. Establishing baseline is important. I would also do the HOS on a
specimen prior to onset of female stimulation for oocyte retrieval.
2) Does anyone feel any optimism that testis biopsy might yield motile
sperm which could then be used in an ICSI procedure? If the results from HOS
indicate viable sperm then my optimism for motile sperm in a biopsy would be
increased. To establish if the pts seminal plasma might contribute to sperm
stasis I would have him collect in media and also expose washed control
sperm with the pts seminal plasma.
Good luck!
Christopher De Jonge, Ph.D., HCLD
dejonge@tc.umn.edu
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