Androlog Mail:
On these Androlog pages there were some questions related to the molecular
link of pesticides to infertility of the exposed farmer -- so that he could
be properly treated. We have similar but more general concerns here in
Central New York because of our vast agricultural commitments of the land.
Farmers coming here for infertility treatment may have used a number of
different pesticides. The EPA has plans to evaluate some 87,000 chemicals
for their potential to disrupt hormones in human and wildlife, screening
through eight preliminary assays to pin down their probable endocrinal
"connection".
The following references may be of interest:
1. Kelce WR et al: Environmental hormone disruptors:Evidence that
vinclozolin developmental toxicity is mediated by antiandrogenic
metabolites. Toxicol Appl Pharmacol 1994;126:276-285.
2. Gray LE Jr:Chemically induced alteration in sexual and functional
development. In, Colburn T, Clement C(eds):The Wildlife/Human Connection.
Princeton, NJ, Princeton Scientific, 1992
3. Lamb EJ, Bennett S: Epidemiological studies of male factors in
Infertility. Ann NY Acad Sci 1994; 709:165-178 (there might have been
another meeting at NY Acad of Sc on this topic earlier this year)
Sid Sarkar, PhD
Department of Pathology
SUNY Health Science Center University Hospital Rm 5720
Syracuse, NY 13210
sarkars@vax.cs.hscsyr.edu
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