Androlog Mail:
In regard to recurrent priapism,
I also had a similar patient. Lupron depot is certainly one approach. Irwin
Goldstein is about to publish another. This is Digoxin.
Therapy consists of an initial loading dose of 0.25 mg qid for one day.
Following this loading dose the patient receives 0.25 mg qd from then on. The
presumed mechanism is an increase in intracellular calcium with resultant
vasoconstriction and intracorporeal smooth muscle contraction. The end point
of this therapy, as with Lupron, is not yet known. At this time Dr. Goldstein
is recommending, depending on the age of the patient and associated co-
morbidities, that they first be evaluated by their internist,(evaluation
including an EKG), prior to instituting this therapy.
My patient who is a 39 yo male s/p multiple shunting procedures has been
maintained on Digoxin after an initial successful intervention with Lupron.
He has been without priapism for 5 months, (the last 2 on Digoxin), and is
still able to have intercourse.
Thomas Jaffe, M.D.
Stept and Arnheim Urologic Associates
Pittsburgh, PA
TMJaffe@aol.com
This archive was generated by hypermail 2.1.2 : Mon Jun 11 2001 - 22:44:35 CDT